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Genetic and pharmacological inhibition of vanin-1 activity in animal models of type 2 diabetes

Vanins are enzymes that convert pantetheine to pantothenic acid (vitamin B5). Insights into the function of vanins have evolved lately, indicating vanin-1 to play a role in inflammation, oxidative stress and cell migration. Moreover, vanin-1 has recently gained attention as a novel modulator of hepa...

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Publicado no:Sci Rep
Main Authors: van Diepen, Janna A., Jansen, Patrick A., Ballak, Dov B., Hijmans, Anneke, Rutjes, Floris P.J.T., Tack, Cees J., Netea, Mihai G., Schalkwijk, Joost, Stienstra, Rinke
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773925/
https://ncbi.nlm.nih.gov/pubmed/26932716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21906
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