Activation of Proteinase 3 Contributes to Nonalcoholic Fatty Liver Disease and Insulin Resistance

Activation of inflammatory pathways is known to accompany development of obesity-induced nonalcoholic fatty liver disease (NAFLD), insulin resistance and type 2 diabetes. In addition to caspase-1, the neutrophil serine proteases proteinase 3, neutrophil elastase and cathepsin G are able to process t...

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Vydáno v:Mol Med
Hlavní autoři: Toonen, Erik JM, Mirea, Andreea-Manuela, Tack, Cees J, Stienstra, Rinke, Ballak, Dov B, van Diepen, Janna A, Hijmans, Anneke, Chavakis, Triantafyllos, Dokter, Wim H, Pham, Christine TN, Netea, Mihai G, Dinarello, Charles A, Joosten, Leo AB
Médium: Artigo
Jazyk:Inglês
Vydáno: Feinstein Institute for Medical Research 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004724/
https://ncbi.nlm.nih.gov/pubmed/27261776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00033
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