Activation of Proteinase 3 Contributes to Nonalcoholic Fatty Liver Disease and Insulin Resistance

Activation of inflammatory pathways is known to accompany development of obesity-induced nonalcoholic fatty liver disease (NAFLD), insulin resistance and type 2 diabetes. In addition to caspase-1, the neutrophil serine proteases proteinase 3, neutrophil elastase and cathepsin G are able to process t...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Toonen, Erik JM, Mirea, Andreea-Manuela, Tack, Cees J, Stienstra, Rinke, Ballak, Dov B, van Diepen, Janna A, Hijmans, Anneke, Chavakis, Triantafyllos, Dokter, Wim H, Pham, Christine TN, Netea, Mihai G, Dinarello, Charles A, Joosten, Leo AB
Formato: Artigo
Idioma:Inglês
Publicado em: Feinstein Institute for Medical Research 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004724/
https://ncbi.nlm.nih.gov/pubmed/27261776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00033
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