MAP3K8 (TPL2/COT) Affects Obesity-Induced Adipose Tissue Inflammation without Systemic Effects in Humans and in Mice

Chronic low-grade inflammation in adipose tissue often accompanies obesity, leading to insulin resistance and increasing the risk for metabolic diseases. MAP3K8 (TPL2/COT) is an important signal transductor and activator of pro-inflammatory pathways that has been linked to obesity-induced adipose ti...

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Detalhes bibliográficos
Main Authors: Ballak, Dov B., van Essen, Peter, van Diepen, Janna A., Jansen, Henry, Hijmans, Anneke, Matsuguchi, Tetsuya, Sparrer, Helmut, Tack, Cees J., Netea, Mihai G., Joosten, Leo A. B., Stienstra, Rinke
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933658/
https://ncbi.nlm.nih.gov/pubmed/24586913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089615
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