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Regulatory T-Cell (Treg) Hybridoma as a Novel Tool to Study Foxp3 Regulation and Treg Fate
The CD25(+)Foxp3(+) regulatory T-cells (Treg) that had lost CD25 and Foxp3 in vivo (ex-Treg) exist but are difficult to study. We generated antigen (Ag)-specific Treg hybridomas from iTreg clones (iTreg-hyb) using iTreg of DO11.10.Foxp3-GFP mice and presented evidence that they behave like ex-Treg....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173573/ https://ncbi.nlm.nih.gov/pubmed/21621978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2011.05.008 |
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