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Rapid and Selective Expansion of Nonclonotypic T Cells in Regulatory T Cell-Deficient, Foreign Antigen-Specific TCR-Transgenic Scurfy Mice: Antigen-Dependent Expansion and TCR Analysis

Foreign Ag-specific TCR-transgenic (Tg) mice contain a small fraction of T cells bearing the endogenous Vβ and Vα chains as well as a population expressing an intermediate level of Tg TCR. Importantly, these minor nonclonotypic populations contain ≥99% of the CD4(+)Foxp3(+) regulatory T cells (Treg)...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Sharma, Rahul, Ju, Angela Chiao-Ying, Kung, John T., Fu, Shu Man, Ju, Shyr-Te
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734502/
https://ncbi.nlm.nih.gov/pubmed/18981113
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