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Pervasive and stochastic changes in the TCR repertoire of regulatory T-cell-deficient mice
We hypothesize that regulatory T-cell (Treg)-deficient strains have an altered TCR repertoire in part due to the expansion of autoimmune repertoire by self-antigen. We compared the Vβ family expression profile between B6 and Treg-lacking B6.Cg-Foxp3(sf)(/Y) (B6.sf) mice using fluorescent anti-Vβ mAb...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841480/ https://ncbi.nlm.nih.gov/pubmed/18310063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxn017 |
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