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Genetic control of the inflammatory T-cell response in regulatory T-cell deficient scurfy mice
IPEX (Immunodysregulation, polyendocrinopathy, enteropathy, X-linked) syndrome is a rare, recessive disorder in patients with mutations in the foxp3 gene, the normal expression of which is required for the generation of functional regulatory T-cells. Scurfy mice also bear a mutation in the foxp3, an...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916692/ https://ncbi.nlm.nih.gov/pubmed/20452830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2010.04.004 |
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