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Large Functional Repertoire of Regulatory T Cell Suppressible Autoimmune T Cells in Scurfy Mice

Scurfy mice, a strain lacking functional Foxp3 transcription factor and CD4(+)CD25(+)Foxp3(+) regulatory T (Treg) cells, spontaneously develop autoimmune responses against skin, lung, liver and tail. However, many organs/tissues are spared from autoimmune attack. Here, we demonstrate that scurfy mic...

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Bibliografski detalji
Glavni autori: Sharma, Rahul, Jarjour, Wael N., Zheng, Lingjie, Gaskin, Felicia, Fu, Shu Man, Ju, Shyr-Te
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099300/
https://ncbi.nlm.nih.gov/pubmed/17521882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2007.04.001
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