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Large Functional Repertoire of Regulatory T Cell Suppressible Autoimmune T Cells in Scurfy Mice
Scurfy mice, a strain lacking functional Foxp3 transcription factor and CD4(+)CD25(+)Foxp3(+) regulatory T (Treg) cells, spontaneously develop autoimmune responses against skin, lung, liver and tail. However, many organs/tissues are spared from autoimmune attack. Here, we demonstrate that scurfy mic...
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| Main Authors: | , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2007
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2099300/ https://ncbi.nlm.nih.gov/pubmed/17521882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2007.04.001 |
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