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Genetic control of the inflammatory T-cell response in regulatory T-cell deficient scurfy mice

IPEX (Immunodysregulation, polyendocrinopathy, enteropathy, X-linked) syndrome is a rare, recessive disorder in patients with mutations in the foxp3 gene, the normal expression of which is required for the generation of functional regulatory T-cells. Scurfy mice also bear a mutation in the foxp3, an...

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Bibliografiske detaljer
Main Authors: Sharma, Rahul, Ju, Shyr-Te
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916692/
https://ncbi.nlm.nih.gov/pubmed/20452830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2010.04.004
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