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Regulatory T-Cell (Treg) Hybridoma as a Novel Tool to Study Foxp3 Regulation and Treg Fate

The CD25(+)Foxp3(+) regulatory T-cells (Treg) that had lost CD25 and Foxp3 in vivo (ex-Treg) exist but are difficult to study. We generated antigen (Ag)-specific Treg hybridomas from iTreg clones (iTreg-hyb) using iTreg of DO11.10.Foxp3-GFP mice and presented evidence that they behave like ex-Treg....

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Bibliografiske detaljer
Main Authors: Sharma, Rahul, Sung, Sun-Sang J., Ju, Chiao-Ying A., Umesh, S. Deshmukh, Fu, Shu Man, Ju, Shyr-Te
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173573/
https://ncbi.nlm.nih.gov/pubmed/21621978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2011.05.008
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