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NKAP is required for T cell maturation and acquisition of functional competency
Newly generated T cells are unable to respond to antigen/MHC. Rather, post-selection single-positive thymocytes must undergo T cell maturation to gain functional competency and enter the long-lived naive peripheral T cell pool. This process is poorly understood, as no gene specifically required for...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173250/ https://ncbi.nlm.nih.gov/pubmed/21624937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101874 |
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