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NKAP, a novel modulator of Notch signaling, is required for T cell development

T cell development depends on the coordinated interplay between receptor signaling and transcriptional activation/repression. We performed a genetic complementation screen, and identified a novel transcriptional repressor, NKAP. NKAP associates with HDAC3 and is part of a DNA-binding complex, as sho...

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Bibliografiske detaljer
Main Authors: Pajerowski, Anthony G., Nguyen, Chau, Aghajanian, Haig, Shapiro, Michael J., Shapiro, Virginia Smith
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777751/
https://ncbi.nlm.nih.gov/pubmed/19409814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.02.011
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