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NKAP, a novel modulator of Notch signaling, is required for T cell development
T cell development depends on the coordinated interplay between receptor signaling and transcriptional activation/repression. We performed a genetic complementation screen, and identified a novel transcriptional repressor, NKAP. NKAP associates with HDAC3 and is part of a DNA-binding complex, as sho...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777751/ https://ncbi.nlm.nih.gov/pubmed/19409814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.02.011 |
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