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NKAP is required for T cell maturation and acquisition of functional competency

Newly generated T cells are unable to respond to antigen/MHC. Rather, post-selection single-positive thymocytes must undergo T cell maturation to gain functional competency and enter the long-lived naive peripheral T cell pool. This process is poorly understood, as no gene specifically required for...

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Autores principales: Hsu, Fan-Chi, Pajerowski, Anthony G., Nelson-Holte, Molly, Sundsbak, Rhianna, Shapiro, Virginia Smith
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173250/
https://ncbi.nlm.nih.gov/pubmed/21624937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101874
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