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Mechanism of actin filament nucleation by Vibrio VopL and implications for tandem-W domain nucleation
Pathogen proteins targeting the actin cytoskeleton often serve as model systems to understand their more complex eukaryotic analogs. We show that the strong actin filament nucleation activity of Vibrio VopL depends on its three W domains and dimerization through a unique VopL C-terminal domain (VCD)...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173040/ https://ncbi.nlm.nih.gov/pubmed/21873985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2109 |
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