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Structure of a Longitudinal Actin Dimer Assembled by Tandem W Domains – Implications for Actin Filament Nucleation
Actin filament nucleators initiate polymerization in cells in a regulated manner. A common architecture among these molecules consists of tandem W domains that recruit three to four actin subunits to form a polymerization nucleus. We describe a low-resolution crystal structure of an actin dimer asse...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2950660/ https://ncbi.nlm.nih.gov/pubmed/20804767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.08.040 |
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