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Structural Basis of Actin Filament Nucleation by Tandem W Domains

Spontaneous nucleation of actin is very inefficient in cells. To overcome this barrier, cells have evolved a set of actin filament nucleators to promote rapid nucleation and polymerization in response to specific stimuli. However, the molecular mechanism of actin nucleation remains poorly understood...

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Bibliographic Details
Main Authors: Chen, Xiaorui, Ni, Fengyun, Tian, Xia, Kondrashkina, Elena, Wang, Qinghua, Ma, Jianpeng
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780403/
https://ncbi.nlm.nih.gov/pubmed/23727244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.04.028
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