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Structural Basis of Actin Filament Nucleation by Tandem W Domains
Spontaneous nucleation of actin is very inefficient in cells. To overcome this barrier, cells have evolved a set of actin filament nucleators to promote rapid nucleation and polymerization in response to specific stimuli. However, the molecular mechanism of actin nucleation remains poorly understood...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3780403/ https://ncbi.nlm.nih.gov/pubmed/23727244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.04.028 |
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