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Mechanisms of leiomodin 2-mediated regulation of actin filament in muscle cells
Leiomodin (Lmod) is a class of potent tandem-G-actin–binding nucleators in muscle cells. Lmod mutations, deletion, or instability are linked to lethal nemaline myopathy. However, the lack of high-resolution structures of Lmod nucleators in action severely hampered our understanding of their essentia...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4611611/ https://ncbi.nlm.nih.gov/pubmed/26417072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1512464112 |
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