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Leiomodin is an Actin Filament Nucleator in Muscle Cells

Initiation of actin polymerization in cells requires nucleation factors. Here we describe an actin-binding protein, leiomodin, which acted as a strong filament nucleator in muscle cells. Leiomodin shared two actin-binding sites with the filament pointed-end capping protein tropomodulin; a flexible N...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chereau, David, Boczkowska, Malgorzata, Skwarek-Maruszewska, Aneta, Fujiwara, Ikuko, Hayes, David B., Rebowski, Grzegorz, Lappalainen, Pekka, Pollard, Thomas D., Dominguez, Roberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845909/
https://ncbi.nlm.nih.gov/pubmed/18403713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1155313
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