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Mechanism of actin filament nucleation by Vibrio VopL and implications for tandem-W domain nucleation
Pathogen proteins targeting the actin cytoskeleton often serve as model systems to understand their more complex eukaryotic analogs. We show that the strong actin filament nucleation activity of Vibrio VopL depends on its three W domains and dimerization through a unique VopL C-terminal domain (VCD)...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173040/ https://ncbi.nlm.nih.gov/pubmed/21873985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2109 |
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