Mechanism of actin filament nucleation by Vibrio VopL and implications for tandem-W domain nucleation

Pathogen proteins targeting the actin cytoskeleton often serve as model systems to understand their more complex eukaryotic analogs. We show that the strong actin filament nucleation activity of Vibrio VopL depends on its three W domains and dimerization through a unique VopL C-terminal domain (VCD)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Namgoong, Suk, Boczkowska, Malgorzata, Glista, Michael J., Winkelman, Jonathan D., Rebowski, Grzegorz, Kovar, David R., Dominguez, Roberto
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173040/
https://ncbi.nlm.nih.gov/pubmed/21873985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2109
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