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The bacterial virulence factors VopL and VopF nucleate actin from the pointed end

VopL and VopF (VopL/F) are tandem WH2-domain actin assembly factors used by infectious Vibrio species to induce actin assembly in host cells. There is disagreement about the filament assembly mechanism of VopL/F, including whether they associate with the filament barbed or pointed end. Here, we used...

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Publicat a:J Cell Biol
Autors principals: Burke, Thomas A., Harker, Alyssa J., Dominguez, Roberto, Kovar, David R.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412564/
https://ncbi.nlm.nih.gov/pubmed/28363971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201608104
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