Structure and specificity of nuclear receptor–coactivator interactions

Combinatorial regulation of transcription implies flexible yet precise assembly of multiprotein regulatory complexes in response to signals. Biochemical and crystallographic analyses revealed that hormone binding leads to the formation of a hydrophobic groove within the ligand binding domain (LBD) o...

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Detalles Bibliográficos
Publicado en:Genes Dev
Autores principales: Darimont, Beatrice D., Wagner, Richard L., Apriletti, James W., Stallcup, Michael R., Kushner, Peter J., Baxter, John D., Fletterick, Robert J., Yamamoto, Keith R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1998
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317236/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9808622/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.21.3343
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