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Thyroid hormone receptor-binding protein, an LXXLL motif-containing protein, functions as a general coactivator

Nuclear hormone receptors activate gene transcription through ligand-dependent association with coactivators. Specific LXXLL sequence motifs present in these cofactors are sufficient to mediate these ligand-induced interactions. A thyroid hormone receptor (TR)-binding protein (TRBP) was cloned by a...

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Detalhes bibliográficos
Main Authors: Ko, Lan, Cardona, Guemalli R., Chin, William W.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18584/
https://ncbi.nlm.nih.gov/pubmed/10823961
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