Thyroid hormone receptor-binding protein, an LXXLL motif-containing protein, functions as a general coactivator

Nuclear hormone receptors activate gene transcription through ligand-dependent association with coactivators. Specific LXXLL sequence motifs present in these cofactors are sufficient to mediate these ligand-induced interactions. A thyroid hormone receptor (TR)-binding protein (TRBP) was cloned by a...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Ko, Lan, Cardona, Guemalli R., Chin, William W.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 2000
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18584/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10823961/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.11.6212
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