Structure and specificity of nuclear receptor–coactivator interactions

Combinatorial regulation of transcription implies flexible yet precise assembly of multiprotein regulatory complexes in response to signals. Biochemical and crystallographic analyses revealed that hormone binding leads to the formation of a hydrophobic groove within the ligand binding domain (LBD) o...

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Bibliografische gegevens
Gepubliceerd in:Genes Dev
Hoofdauteurs: Darimont, Beatrice D., Wagner, Richard L., Apriletti, James W., Stallcup, Michael R., Kushner, Peter J., Baxter, John D., Fletterick, Robert J., Yamamoto, Keith R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 1998
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317236/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9808622/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.21.3343
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