Structure and specificity of nuclear receptor–coactivator interactions

Combinatorial regulation of transcription implies flexible yet precise assembly of multiprotein regulatory complexes in response to signals. Biochemical and crystallographic analyses revealed that hormone binding leads to the formation of a hydrophobic groove within the ligand binding domain (LBD) o...

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Bibliografski detalji
Glavni autori: Darimont, Beatrice D., Wagner, Richard L., Apriletti, James W., Stallcup, Michael R., Kushner, Peter J., Baxter, John D., Fletterick, Robert J., Yamamoto, Keith R.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 1998
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC317236/
https://ncbi.nlm.nih.gov/pubmed/9808622
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