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Structure and specificity of nuclear receptor–coactivator interactions

Combinatorial regulation of transcription implies flexible yet precise assembly of multiprotein regulatory complexes in response to signals. Biochemical and crystallographic analyses revealed that hormone binding leads to the formation of a hydrophobic groove within the ligand binding domain (LBD) o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes Dev
Prif Awduron: Darimont, Beatrice D., Wagner, Richard L., Apriletti, James W., Stallcup, Michael R., Kushner, Peter J., Baxter, John D., Fletterick, Robert J., Yamamoto, Keith R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 1998
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317236/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9808622/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.21.3343
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