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Developmental timing of CCM2 loss influences cerebral cavernous malformations in mice
Cerebral cavernous malformations (CCM) are vascular malformations of the central nervous system (CNS) that lead to cerebral hemorrhages. Familial CCM occurs as an autosomal dominant condition caused by loss-of-function mutations in one of the three CCM genes. Constitutive or tissue-specific ablation...
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| Glavni autori: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171098/ https://ncbi.nlm.nih.gov/pubmed/21859843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110571 |
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