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KLF4 is a key determinant in the development and progression of cerebral cavernous malformations

Cerebral cavernous malformations (CCMs) are vascular malformations located within the central nervous system often resulting in cerebral hemorrhage. Pharmacological treatment is needed, since current therapy is limited to neurosurgery. Familial CCM is caused by loss‐of‐function mutations in any of C...

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Библиографические подробности
Опубликовано в: :EMBO Mol Med
Главные авторы: Cuttano, Roberto, Rudini, Noemi, Bravi, Luca, Corada, Monica, Giampietro, Costanza, Papa, Eleanna, Morini, Marco Francesco, Maddaluno, Luigi, Baeyens, Nicolas, Adams, Ralf H, Jain, Mukesh K, Owens, Gary K, Schwartz, Martin, Lampugnani, Maria Grazia, Dejana, Elisabetta
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718159/
https://ncbi.nlm.nih.gov/pubmed/26612856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505433
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