KLF4 is a key determinant in the development and progression of cerebral cavernous malformations

Cerebral cavernous malformations (CCMs) are vascular malformations located within the central nervous system often resulting in cerebral hemorrhage. Pharmacological treatment is needed, since current therapy is limited to neurosurgery. Familial CCM is caused by loss‐of‐function mutations in any of C...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Cuttano, Roberto, Rudini, Noemi, Bravi, Luca, Corada, Monica, Giampietro, Costanza, Papa, Eleanna, Morini, Marco Francesco, Maddaluno, Luigi, Baeyens, Nicolas, Adams, Ralf H, Jain, Mukesh K, Owens, Gary K, Schwartz, Martin, Lampugnani, Maria Grazia, Dejana, Elisabetta
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718159/
https://ncbi.nlm.nih.gov/pubmed/26612856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505433
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