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Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways

In Drosophila, planar cell polarity (PCP) signaling is mediated by the receptor Frizzled (Fz) and transduced by Dishevelled (Dsh). Wingless (Wg) signaling also requires Dsh and may utilize DFz2 as a receptor. Using a heterologous system, we show that Dsh is recruited selectively to the membrane by F...

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Dettagli Bibliografici
Pubblicato in:Genes Dev
Autori principali: Axelrod, Jeffrey D., Miller, Jeffrey R., Shulman, Joshua M., Moon, Randall T., Perrimon, Norbert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317102/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9716412/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.16.2610
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