Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways

In Drosophila, planar cell polarity (PCP) signaling is mediated by the receptor Frizzled (Fz) and transduced by Dishevelled (Dsh). Wingless (Wg) signaling also requires Dsh and may utilize DFz2 as a receptor. Using a heterologous system, we show that Dsh is recruited selectively to the membrane by F...

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Εκδόθηκε σε:	Genes Dev
Κύριοι συγγραφείς:	Axelrod, Jeffrey D., Miller, Jeffrey R., Shulman, Joshua M., Moon, Randall T., Perrimon, Norbert
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Cold Spring Harbor Laboratory Press 1998
Θέματα:	Research Paper
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317102/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9716412/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.16.2610
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