Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways

In Drosophila, planar cell polarity (PCP) signaling is mediated by the receptor Frizzled (Fz) and transduced by Dishevelled (Dsh). Wingless (Wg) signaling also requires Dsh and may utilize DFz2 as a receptor. Using a heterologous system, we show that Dsh is recruited selectively to the membrane by F...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Axelrod, Jeffrey D., Miller, Jeffrey R., Shulman, Joshua M., Moon, Randall T., Perrimon, Norbert
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 1998
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317102/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9716412/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.16.2610
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