Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways

In Drosophila, planar cell polarity (PCP) signaling is mediated by the receptor Frizzled (Fz) and transduced by Dishevelled (Dsh). Wingless (Wg) signaling also requires Dsh and may utilize DFz2 as a receptor. Using a heterologous system, we show that Dsh is recruited selectively to the membrane by F...

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Detalles Bibliográficos

Publicado en:	Genes Dev
Autores principales:	Axelrod, Jeffrey D., Miller, Jeffrey R., Shulman, Joshua M., Moon, Randall T., Perrimon, Norbert
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Cold Spring Harbor Laboratory Press 1998
Materias:	Research Paper
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317102/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9716412/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.16.2610
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