naked cuticle targets dishevelled to antagonize Wnt signal transduction

In Drosophila embryos the protein Naked cuticle (Nkd) limits the effects of the Wnt signal Wingless (Wg) during early segmentation. nkd loss of function results in segment polarity defects and embryonic death, but how nkd affects Wnt signaling is unknown. Using ectopic expression, we find that Nkd a...

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Bibliografische gegevens
Hoofdauteurs: Rousset, Raphaël, Mack, Judith A., Wharton, Keith A., Axelrod, Jeffrey D., Cadigan, Ken M., Fish, Matthew P., Nusse, Roel, Scott, Matthew P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2001
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC312650/
https://ncbi.nlm.nih.gov/pubmed/11274052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.869201
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