naked cuticle targets dishevelled to antagonize Wnt signal transduction

In Drosophila embryos the protein Naked cuticle (Nkd) limits the effects of the Wnt signal Wingless (Wg) during early segmentation. nkd loss of function results in segment polarity defects and embryonic death, but how nkd affects Wnt signaling is unknown. Using ectopic expression, we find that Nkd a...

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Bibliografske podrobnosti
Main Authors: Rousset, Raphaël, Mack, Judith A., Wharton, Keith A., Axelrod, Jeffrey D., Cadigan, Ken M., Fish, Matthew P., Nusse, Roel, Scott, Matthew P.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2001
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC312650/
https://ncbi.nlm.nih.gov/pubmed/11274052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.869201
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