naked cuticle targets dishevelled to antagonize Wnt signal transduction

In Drosophila embryos the protein Naked cuticle (Nkd) limits the effects of the Wnt signal Wingless (Wg) during early segmentation. nkd loss of function results in segment polarity defects and embryonic death, but how nkd affects Wnt signaling is unknown. Using ectopic expression, we find that Nkd a...

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Main Authors: Rousset, Raphaël, Mack, Judith A., Wharton, Keith A., Axelrod, Jeffrey D., Cadigan, Ken M., Fish, Matthew P., Nusse, Roel, Scott, Matthew P.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2001
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Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC312650/
https://ncbi.nlm.nih.gov/pubmed/11274052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.869201
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