Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways

In Drosophila, planar cell polarity (PCP) signaling is mediated by the receptor Frizzled (Fz) and transduced by Dishevelled (Dsh). Wingless (Wg) signaling also requires Dsh and may utilize DFz2 as a receptor. Using a heterologous system, we show that Dsh is recruited selectively to the membrane by F...

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Bibliografske podrobnosti

izdano v:	Genes Dev
Principais autores:	Axelrod, Jeffrey D., Miller, Jeffrey R., Shulman, Joshua M., Moon, Randall T., Perrimon, Norbert
Format:	Artigo
Jezik:	Inglês
Izdano:	Cold Spring Harbor Laboratory Press 1998
Teme:	Research Paper
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317102/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9716412/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.16.2610
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