Cleavage of the death domain kinase RIP by Caspase-8 prompts TNF-induced apoptosis
Although the molecular mechanisms of TNF signaling have been largely elucidated, the principle that regulates the balance of life and death is still unknown. We report here that the death domain kinase RIP, a key component of the TNF signaling complex, was cleaved by Caspase-8 in TNF-induced apoptos...
محفوظ في:
| الحاوية / القاعدة: | Genes Dev |
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| المؤلفون الرئيسيون: | , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Cold Spring Harbor Laboratory Press
1999
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317073/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10521396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.19.2514 |
| الوسوم: |
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