Cleavage of the death domain kinase RIP by Caspase-8 prompts TNF-induced apoptosis

Although the molecular mechanisms of TNF signaling have been largely elucidated, the principle that regulates the balance of life and death is still unknown. We report here that the death domain kinase RIP, a key component of the TNF signaling complex, was cleaved by Caspase-8 in TNF-induced apoptos...

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Argitaratua izan da:	Genes Dev
Egile Nagusiak:	Lin, Yong, Devin, Anne, Rodriguez, Yolanda, Liu, Zheng-gang
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Cold Spring Harbor Laboratory Press 1999
Gaiak:	Research Paper
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317073/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10521396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.19.2514
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