Cleavage of the death domain kinase RIP by Caspase-8 prompts TNF-induced apoptosis

Although the molecular mechanisms of TNF signaling have been largely elucidated, the principle that regulates the balance of life and death is still unknown. We report here that the death domain kinase RIP, a key component of the TNF signaling complex, was cleaved by Caspase-8 in TNF-induced apoptos...

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Библиографические подробности

Опубликовано в::	Genes Dev
Главные авторы:	Lin, Yong, Devin, Anne, Rodriguez, Yolanda, Liu, Zheng-gang
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Cold Spring Harbor Laboratory Press 1999
Предметы:	Research Paper
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317073/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10521396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.19.2514
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