Cleavage of the death domain kinase RIP by Caspase-8 prompts TNF-induced apoptosis

Although the molecular mechanisms of TNF signaling have been largely elucidated, the principle that regulates the balance of life and death is still unknown. We report here that the death domain kinase RIP, a key component of the TNF signaling complex, was cleaved by Caspase-8 in TNF-induced apoptos...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Lin, Yong, Devin, Anne, Rodriguez, Yolanda, Liu, Zheng-gang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 1999
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317073/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10521396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.19.2514
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