Cleavage of the death domain kinase RIP by Caspase-8 prompts TNF-induced apoptosis

Although the molecular mechanisms of TNF signaling have been largely elucidated, the principle that regulates the balance of life and death is still unknown. We report here that the death domain kinase RIP, a key component of the TNF signaling complex, was cleaved by Caspase-8 in TNF-induced apoptos...

Celý popis

Podrobná bibliografie

Vydáno v:	Genes Dev
Hlavní autoři:	Lin, Yong, Devin, Anne, Rodriguez, Yolanda, Liu, Zheng-gang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Cold Spring Harbor Laboratory Press 1999
Témata:	Research Paper
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317073/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10521396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.19.2514
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!