The Death Domain Kinase RIP Is Essential for TRAIL (Apo2L)-Induced Activation of IκB Kinase and c-Jun N-Terminal Kinase

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) (Apo2 ligand [Apo2L]) is a member of the TNF superfamily and has been shown to have selective antitumor activity. Although it is known that TRAIL (Apo2L) induces apoptosis and activates NF-κB and Jun N-terminal kinase (JNK) throug...

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Detalhes bibliográficos
Main Authors: Lin, Yong, Devin, Anne, Cook, Amy, Keane, Maccon M., Kelliher, Michelle, Lipkowitz, Stanley, Liu, Zheng-gang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86162/
https://ncbi.nlm.nih.gov/pubmed/10958661
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