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Chemical Modification of siRNA Bases to Probe and Enhance RNA Interference

Considerable attention has focused on the use of alternatives to the native ribose and phosphate backbone of small interfering RNAs for therapeutic applications of the RNA interference pathway. In this synopsis, we highlight the less common chemical modifications, namely those of the RNA nucleobases...

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Bibliografische gegevens
Hoofdauteurs: Peacock, Hayden, Kannan, Arunkumar, Beal, Peter A., Burrows, Cynthia J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170502/
https://ncbi.nlm.nih.gov/pubmed/21834582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo2012225
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