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Chemical Modification of siRNA Bases to Probe and Enhance RNA Interference
Considerable attention has focused on the use of alternatives to the native ribose and phosphate backbone of small interfering RNAs for therapeutic applications of the RNA interference pathway. In this synopsis, we highlight the less common chemical modifications, namely those of the RNA nucleobases...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3170502/ https://ncbi.nlm.nih.gov/pubmed/21834582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo2012225 |
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