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Tuning RNA Interference by Enhancing siRNA/PAZ Recognition
[Image: see text] Chemically modified siRNAs were synthesized to enhance the corresponding silencing activities. The introduced modifications endowed siRNAs with high silencing effect, long RNAi persistence, and better serum resistance. Theoretical data allowed us to correlate the observed siRNAs in...
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| Main Authors: | , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027432/ https://ncbi.nlm.nih.gov/pubmed/24900566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300284b |
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