Tuning RNA Interference by Enhancing siRNA/PAZ Recognition

[Image: see text] Chemically modified siRNAs were synthesized to enhance the corresponding silencing activities. The introduced modifications endowed siRNAs with high silencing effect, long RNAi persistence, and better serum resistance. Theoretical data allowed us to correlate the observed siRNAs in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gaglione, Maria, Potenza, Nicoletta, Di Fabio, Giovanni, Romanucci, Valeria, Mosca, Nicola, Russo, Aniello, Novellino, Ettore, Cosconati, Sandro, Messere, Anna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2012
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027432/
https://ncbi.nlm.nih.gov/pubmed/24900566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300284b
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