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The cytotoxic ribonuclease onconase targets RNA interference (siRNA)
Onconase (Onc), a ribonuclease from oocytes of Northern Leopard frogs (Rana pipienss) is cytostatic and cytotoxic to a variety of tumor lines in vitro, inhibits growth of tumors in animal in vivo models and enhances sensitivity of tumor cells to a number of other cytotoxic agents with diverse mechan...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586937/ https://ncbi.nlm.nih.gov/pubmed/18927512 |
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